Engelsk titel: Inflammatory bowel disease often cause anemia and iron deficiency
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Författare:
Halfvarson, Jonas
Email: jonas.halfvarson@orebroll.se
Språk: Swe
Antal referenser: 9
Dokumenttyp:
Översikt
UI-nummer: 15047016
Sammanfattning
Anaemia is the most common systemic complication in inflammatory bowel disease (IBD), having profound effects on the quality of life
in affected individuals. Approximately 6–30% of patients with IBD fulfil the criteria of anaemia. The aetiologies of anaemia in IBD are several,
with iron deficiency and anaemia due to chronic inflammation (functional iron deficiency) being the most prevalent. Iron deficiency anaemia
in patients with IBD may result from chronic blood loss, reduced iron absorption and the chronic inflammation itself, the latter inhibiting the
recirculation of iron and thereby the homeostasis of iron metabolism. Iron supplementation should be commenced in patients with anaemia
and proven iron deficiency, either as oral or as intravenous replacement. In general, intravenous administration is advisable in iron-
deficient patients who are intolerant or unresponsive to oral supplementation, for patients with severe anaemia or pronounced disease
activity. In addition, the underlying cause should be treated to prevent further iron loss.