Sammanfattning
OBJECTIVE: To evaluate the effect of constraint-induced movement therapy in adult stroke
patients and to examine the impact of time since stroke and various treatment modalities.
DATA SOURCES: PubMed, EMBASE, Cochrane and PEDro trial registers were searched for clinical
trials published before November 2012.
STUDY SELECTION: Randomized or quasi-randomized controlled trials of constraint-induced
movement therapy lasting 2-7 h/day for 8–28 days were included.
DATA EXTRACTION: Measurements were classified into the following categories: arm motor function,
arm motor activity, activities of daily living, and participation. A pooled standardized mean difference
(SMD) was calculated for each category. Moderators were: trial quality, behavioural techniques,
amount of training, time since stroke, shaping, and the nature of the control group.
DATA SYNTHESIS: Of 3842 records initially screened 23 trials were included. A small post-treatment
effect was found on arm motor function (SMD 0.28, 95% confidence interval (CI) 0.11-0.44).
Meanwhile, a moderate effect on arm motor activity was found post-treatment (SMD 0.51, 95% CI 0.30
-0.73) and at 3-6 months follow-up (SMD 0.41, 95% CI 0.08-0.74).
CONCLUSION: Constraint-induced movement therapy can improve arm motor function and improve
arm motor activities and may have a lasting effect on arm motor activity.