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Oxidativt stress kan vaere en mulig årsag til metastasering hos patienter med kolorektal cancer
Engelsk titel: Oxidative stress may cause metastatic disease in patients with colorectal cancer Läs online Författare: Söndergaard, Edith Smed ; Gögenur, Ismail Språk: Dan Antal referenser: 30 Dokumenttyp: Översikt UI-nummer: 15067301

Tidskrift

Ugeskrift for Laeger 2015;177(9)857-60 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Despite surgical treatment of stage II colorectal cancer many patients will experience relapse. Inflammatory and immunologic reactions created due to the surgical stress response result in the production of reactive oxygen species. Oxidative stress in turn, may result in the stimulation of cancer cells that have not been cleared by the immune system to metastasize. In this paper we present an overview of studies where oxidative stress in relation to surgery has been linked to the development of metastatic disease.