Cardiovascular risk factors in 2011 and secular trends since 2007: the Cardiovascular Risk in
Young Finns Study
Engelsk titel: Cardiovascular risk factors in 2011 and secular trends since 2007: the Cardiovascular Risk in
Young Finns Study
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Författare:
Nuotio, Joel
;
Oikonen, Mervi
;
Magnussen, Costan G
;
Jokinen, Eero
;
Laitinen, Tomi
;
Hutri-Kähönen, Nina
;
Kähönen, Mika
;
Lehtimäki, Terho
;
Taittonen, Leena
;
Tossavainen, Päivi
;
Jula, Antti
;
Loo, Britt-Marie
;
Viikari, Jorma Sa
;
Raitakari, Olli T
;
Juonala, Markus
Email: jovanu@utu.fi
Språk: Eng
Antal referenser: 30
Dokumenttyp:
Artikel
UI-nummer: 15069438
Sammanfattning
Aims: Cardiovascular risk factor levels in 2011 and 4-year changes between 2007 and 2011
were examined using data collected in follow-ups of the Cardiovascular Risk in Young Finns Study.
Methods: The study population comprised 2063 Finnish adults aged 34-49 years (45% male). Lipid
and blood pressure levels, glucose and anthropometry were measured and life style risk factors
examined with questionnaires. Results: Mean total cholesterol level in 2011 was 5.19 mmol/l, low
density lipoprotein (LDL)-cholesterol 3.27 mmol/l, high density lipoprotein (HDL)-cholesterol 1.33
mmol/l, and triglycerides 1.34 mmol/l. Using American Diabetes Association criteria, Type 2 diabetes
(T2D) was observed in 4.1% and prediabetes (fasting glucose 5.6-6.9 mmol/l or glycated hemoglobin
5.7-6.4%) diagnosed for 33.8% of the participants. Significant changes (P < 0.05) between 2007 and
2011 included an increase in waist circumference (3.3%) in women. In both sexes, systolic (-3.0% in
women, -4.0% in men) and diastolic (-3.0% in women, -3.3% in men) blood pressure and triglycerides
(-3.4% in women, -6.5% in men) decreased during follow-up. Conclusions: Previously observed
favorable trends in LDL-cholesterol levels have leveled off among a sample of young and middle-
aged adults in Finland. Triglyceride and blood pressure levels have decreased. Over one-third of the
study population had prediabetes and may be at increased risk for T2D.