Engelsk titel: Effects of comorbid anxiety disorders on the course of bipolar disorder-I
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Författare:
Buturak, Sadiye Visal
;
Kocak, Orhan Murat
Email: visalbuturak@hotmail.com
Språk: Eng
Antal referenser: 30
Dokumenttyp:
Artikel
UI-nummer: 15113679
Sammanfattning
Background and aims: Although comorbid anxiety disorders (AD) are quite frequent in bipolar
disorders (BD), data on how this comorbidity affects BD are limited. In the present study, we aimed to
investigate the frequency of comorbid AD in Turkish patients with bipolar disorder-I (BD-I) and the
effects of comorbid AD on the course of BD-I. Methods: 114 patients with BD-I were included in the
study. All patients were diagnosed by a psychiatrist. The patients were divided into two groups as
BD-I patients with lifetime comorbid AD (BDI-CAD) or those without comorbid AD (BDI). Results: 37
(32.46%) patients had one or more comorbid lifetime AD. The numbers of admissions to the outpatient
clinic within calendar year 2013 (P = 0.014), the number of lifetime mood episodes (P = 0.019) and the
duration of BD (P = 0.007) were higher in the BDI-CAD group compared with the BDI group. There was
a strong relationship between the duration of the disorder and the number of episodes (r = 0.583, P <
0.001). Partial correlation analyses showed that the number of admission to the outpatient clinic
correlated significantly with the frequency of episodes (P = 0.007, r = 0.282). Conclusion: We found
that the patients with BDI-CAD use the healthcare system more frequently than the BDI patients. This
suggests that AD comorbidity may have a negative influence on the course of BD-I and it is a factor
that should be considered in the clinical follow-up.