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Behandling med inhalationssteroid öger risiko for pneumoni ved kronisk obstruktiv lungesygdom
Engelsk titel: Inhaled corticosteroid treatment increases the risk of pneumonia in patients with CPOD Läs online Författare: Lumholdt, Mads ; Steenholt, Janni Vagner ; Vestbo, Jörgen Språk: Dan Antal referenser: 19 Dokumenttyp: Översikt UI-nummer: 15117756

Tidskrift

Ugeskrift for Laeger 2015;177(18)1700-3 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Clinical studies have suggested that inhaled corticosteroid (ICS) increases the frequency of pneumonia in patients with chronic obstructive pulmonary disease (COPD). This article summarizes the risk of pneumonia by reviewing the largest clinical studies addressing pneumonia as an adverse effect of ICS treatment. The collected data show that treatment of COPD patients with ICS increases the rate of pneumonia compared with ß2- agonists or placebo. Physicians are recommended to follow guidelines and solely treat COPD patients with ICS if the patients are at high risk of exacerbations.