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Melatonins indvirkning på immunsystem og cancer
Engelsk titel: The influence of melatonin on the immune system and cancer Läs online Författare: Vinther, Anna Gry ; Claesson, Mogens Helweg Språk: Dan Antal referenser: 30 Dokumenttyp: Översikt UI-nummer: 15127851

Tidskrift

Ugeskrift for Laeger 2015;177(20)1899-1902 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Melatonin has been shown to play a fundamental part in neuroimmunomodulation. Besides regulating the circadian rhythm it works as a natural antioxidant with immune sti­mu­latory and anti- cancer properties. Melatonin is a regulator of haemopoiesis and modifies various cells and cytokines of the immune system. Also, melatonin elicits oncostatic properties in a variety of different tumour cell lines. A number of studies have documented that when given in combination with chemo­the­r-a­py to patients with disseminated disease, melatonin increases the overall one-year survival and reduces toxic side effects.