Triglycerider - nygammal riskfaktor för hjärt-kärlsjukdom Subgruppsanalys visar på betydelsen efter akut koronart syndrom
Engelsk titel: Triglycerides - a long known risk factor for cardiovascular disease. Subgroup analysis shows the importance after acute coronary
syndrome
Läs online
Författare:
Olsson, Anders G
Email: anders.olsson@liu.se
Språk: Swe
Antal referenser: 18
Dokumenttyp:
Artikel
UI-nummer: 15127972
Sammanfattning
An increased blood concentration of triglycerides (TG) has long been recognized as an important risk factor for cardiovascular disease.
Through competition from HDL cholesterol and the arrival of statin treatment for high LDL cholesterol the importance of TG as risk factor was
largely forgotten. A high concentration of TG indicates high blood levels of TG-rich lipoproteins including cholesterol rich remnant particles.
Studies using Mendelian randomizations have demonstrated that a low HDL cholesterol does not carry a direct atherogenic function and that
remnant particles do so. New efforts should be exercised in order to diminish residual cardiovascular risk during statin treatment through
decreasing TG rich lipoproteins.