Primär aldosteronism är en underdiagnostiserad orsak till hypertoni. Viktigt hitta odiagnostiserade patienter - effektiv behandling finns
Sammanfattning
Primary aldosteronism is the most common cause of secondary hypertension with an estimated prevalence of 5-13 % among patients with
hypertension. The most common causes are aldosterone producing adrenal adenoma and idiopathic adrenal hyperplasia. Patients with
primary aldosteronism have a higher prevalence of cardiovascular morbidity and mortality compared to patients with essential hypertension.
An effective treatment is available for patients with primary aldosteronism, with mineralocorticoid receptor antagonists in bilateral, and minimal
invasive adrenal surgery in unilateral disease, which emphasizes the importance of early detection, adequate diagnostic work-up and
treatment. In this paper we give a short review of the etiology, pathophysiology, co-morbidities, screening, diagnostic work-up, treatment, and
treatment outcomes of primary aldosteronism.