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Iskaemisk praekonditionering til forebyggelse af reperfusionsskade ved ikkekardial kirurgi
Engelsk titel: Ischaemic preconditioning for protection against reperfusion injury in non-cardiac surgery Läs online Författare: Ekelöf, Sarah ; Gögenur, Ismail Språk: Dan Antal referenser: 24 Dokumenttyp: Översikt UI-nummer: 16017058

Tidskrift

Ugeskrift for Laeger 2015;177(24)2302-5 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift

Sammanfattning

Remote ischaemic preconditioning is a non-invasive intervention that is done by transient occlusion of the blood flow to a limb with a blood pressure cuff. The intervention initiates a systemic endogenous protective response, which may confer multi-organ protection against acute ischaemia reperfusion injury. Originally discovered as a therapeutic strategy in cardiac surgery for protecting the myocardium against ischaemia reperfusion injury, it has been discovered that remote ischaemic preconditioning may confer protection against surgical stress and reperfusion injury in non-cardiac surgery.