Engelsk titel: A safety assessment of Coriolus versicolor biomass as a food supplement
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Författare:
Ferrao, Jorge
;
Fernandes, Tito
;
Barros, Ana B
Email: anabdebarros@gmail.com
Språk: Eng
Antal referenser: 43
Dokumenttyp:
Artikel
UI-nummer: 16033438
Sammanfattning
Background: Coriolus versicolor (CV) is a common mushroom with antitumor, anti-inflammatory,
antioxidant, antiviral, antibacterial, and immunomodulatory properties. The existence of these
properties has been extensively proven mainly using CV extract; research on the biomass form is
scarce.
Objective: The aim of this study was to investigate the safety of the CV biomass form, as it is
commonly used as a food supplement.
Design: CV biomass powder was dissolved in distilled water and administered daily (2.5, 5.0, and 7.5
g/kg live weight) in single doses by gavage to both female and male Charles River albino rats.
Results: No adverse or lethal effects were observed as a consequence of the daily administration of
CV biomass. In addition, compared with the control group, no abnormal findings were observed at
necropsy and histopathological examination.
Conclusions: A safe profile of CV biomass for human consumption can be inferred from the absence
of any remarkable adverse effects in rats.