Rask og effektiv sårtilheling i munnhulen: En rolle for signalmolekyler i saliva?
Engelsk titel: Rapid and scar-free wound healing in the oral cavity: a role of signaling molecules in saliva?
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Författare:
Schenck, Karl
;
Helgeland, Kristen
Email: karl.schenck@odont.uio.no
Språk: Nor
Antal referenser: 45
Dokumenttyp:
Artikel
UI-nummer: 16053663
Sammanfattning
Wound healing is a complex process consisting of a sequence of consecutive events. In the oral
cavity, wounds heal quickly and mostly without scarring, unlike in the skin. One reason for this is the
presence of saliva which contains substances that promote healing. We have examined some of the
effects of the signaling molecules nerve growth factor (NGF) and trefoil family 3 (TFF3) which are
released in saliva. Along with other studies, our findings indicate that these signaling molecules
affect different phases of oral wound healing and that they therefore may be promising candidates for
promoting healing of acute and chronic wounds, both in the oral cavity and the skin.