Sammanfattning
Pre-eclampsia complicates 7% of pregnancies. The heterogeneity of the syndrome makes it difficult to assess its
development and complications, and the current models have low predictive values. Studies indicate a significant difference in
the levels of the angiogenic factors: placental growth factor (PlGF) and soluble fms-like tyrosin kinase 1 (sFlt-1), as well as the
sFlt-1-PlGF ratio in women with preeclampsia compared to women without pre-eclampsia. These angiogenic factors can also be
used to help find the women at risk for complications. However, before implementing PlGF and sFlt-1-PlGF ratio in the diagnosis
and risk assessment, establishment and further validation of cut-offs are needed.