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Angiogenetiske faktorer kan bruges ved mistanke om svangerskabsforgiftning
Engelsk titel: Angiogenic factors can be used when pre-eclampsia is suspected Läs online Författare: Andrea, Mille Kyhn ; Lykke, Jacob Alexander Språk: Dan Antal referenser: 30 Dokumenttyp: Översikt UI-nummer: 16057298

Tidskrift

Ugeskrift for Laeger 2016;178(2)164-9 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Pre-eclampsia complicates 7% of pregnancies. The heterogeneity of the syndrome makes it difficult to assess its development and complications, and the current models have low predictive values. Studies indicate a significant difference in the levels of the angiogenic factors: placental growth factor (PlGF) and soluble fms-like tyrosin kinase 1 (sFlt-1), as well as the sFlt-1-PlGF ratio in women with preeclampsia compared to women without pre-eclampsia. These angiogenic factors can also be used to help find the women at risk for complications. However, before implementing PlGF and sFlt-1-PlGF ratio in the diagnosis and risk assessment, establishment and further validation of cut-offs are needed.