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Betablokkere kan gavne patienter med KOL og hjertesygdom
Engelsk titel: Patients with chronic obstructive pulmonary disease and heart disease can benefit from beta-blocker treatment Läs online Författare: Bech Rasmussen, Daniel ; Lange, Peter ; Jensen, Magnus Thorsten Språk: Dan Antal referenser: 30 Dokumenttyp: Översikt UI-nummer: 16067514

Tidskrift

Ugeskrift for Laeger 2016;178(6)555-9 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Chronic obstructive pulmonary disease (COPD) and coronary heart disease share smoking as the most important com­mon risk factor and there is a high prevalence of cardio­vascular disease among COPD patients. Although cardiose­lective beta- blockers are safe in treatment of COPD, they are often withheld in these patients. In observational studies, beta-blocker treatment is associated with significantly reduced mortality and reduced risk of exacerbations of COPD. This effect may be caused by the beneficial effect of beta-blockers on heart failure, tachycardia and upregulation of beta-receptors in the airways.