Engelsk titel: Mechanism of low-back pain with focus on Modic changes
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Författare:
Bendix, Tom
;
Manniche, Claus
Email: tom.bendix@regionh.dk
Språk: Dan
Antal referenser: 30
Dokumenttyp:
Översikt
UI-nummer: 16087678
Sammanfattning
Low-back pain (LBP) pathology and pain have previously been connected with physical strain. The coping was therefore
characterized by »be careful!« messages. In the 90s it was shown that these physical loads virtually did not mean anything
regarding disc degeneration, although loads may create LBP episodes. Genetic aspects and the demonstration in 2006 that
Modic changes (MC) generally correlated with LBP changed our perception, especially because antibiotics seemed to be effective
in MC. Moreover, the role of cytokines is becoming increasingly clear. The following years will be very exciting.