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Atypisk femurfraktur hos en kvinde i behandling med lamotrigen
Engelsk titel: Atypical femoral fracture in a woman treated with lamotrigine Läs online Författare: Voldby, René Gren Hansen ; Bajalan, Salar Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 16107868

Tidskrift

Ugeskrift for Laeger 2016;178(12)1175-6 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Epileptics are often treated long-term with antiepileptic drugs (AED) of which some are suspected to cause reduction in bone mineral density (BMD). Lamotrigine might not have this effect. In this case report a 51-year-old epileptic woman who had normal BMD level was treated with lamotrigine and sustained an atypical femoral fracture (AFF) after a low-energy trauma. AFF has been associated with treatment with bisphosphonate, but never with treatment with lamotrigine or other AED’s. However, this case report shows that AFF might be associated to treatment with lamotrigine. The possible correlation calls for further investigation.