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Elektrokemoterapi til behandling af kutane metastaser
Engelsk titel: Electrochemotherapy for treatment of cutaneous metastases Läs online Författare: Falk, Hanne ; Wichmann Matthiessen, Louise ; Dahlström, Karin ; Gehl, Julie Språk: Dan Antal referenser: 30 Dokumenttyp: Översikt UI-nummer: 16117889

Tidskrift

Ugeskrift for Laeger 2016;178(13)1243-7 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Cutaneous metastases occur in up to 9% of all patients with cancer and may cause discomfort and stigmatization. Electro­chemotherapy is a local treatment using electric pulses to permeabilize cell membranes, enabling chemotherapy, such as bleomycin, to enter the cells and increase the cytotoxic effect by at least 300-fold. Electrochemotherapy is an efficient, once only treatment for cutaneous metastases with an objective response of 62-99%. Electrochemotherapy can reduce discomfort such as ulceration, oozing, bleeding and pain. Adverse events depend on the size of treatment area, but are very limited.