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Sekundaer binyrebarkinsufficiens under opioidbehandling
Engelsk titel: Secondary adrenal insufficiency during opiate treatment Läs online Författare: Kornholt, Jonatan Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 16127002

Tidskrift

Ugeskrift for Laeger 2016;178(15)1444-5 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

A 25-year-old previously healthy man developed secondary adrenal insufficiency during opiate treatment with tramadol and morphine for upper back pain. He experienced a 10 kg weight loss in six weeks. MRI of the hypothalamus and the pituitary gland ruled out cerebral pathology. After dis­con­tinuation of the opiate treatment the condition normalised. Opiate therapy can cause endocrine dysfunction, and clinicians should always consider adverse drug reactions as a differential diagnosis for unexplained symptoms.