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Brug af tranexamsyre ved övre gastrointestinal blödning
Engelsk titel: Tranexamic acid for upper gastrointestinal bleeding Läs online Författare: Jessing, Thomas Damgaard ; Fenger-Eriksen, Christian Språk: Dan Antal referenser: 21 Dokumenttyp: Översikt UI-nummer: 16127082

Tidskrift

Ugeskrift for Laeger 2016;178(17)1592-5 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Tranexamic acid inhibits the degradation of a newly formed fibrin clot. The drug reduces blood loss and transfusion requirements in a wide range of different clinical scenarios and patient settings. So far, tranexamic acid is not part of standard treatment among patients with gastrointestinal bleeding. This article evaluates the available literature on this topic. Tranexamic acid seems appropriate as adjuvant treatment during upper gastrointestinal bleeding. However, these patients are often old and have several co-morbidities. Therefore, thromboembolic risk and tranexamic acid dosage should be carefully evaluated.