Hudbiopsi og kvantitativ sensorisk testning kan bidrage til diagnostik af småfiberpolyneuropati
Sammanfattning
Nerve conduction studies are normal in small fibre neuropathy and special methods such as skin biopsies or quantitative sensory testing
are required for diagnosis. In skin biopsies, nerve fibres are stained immunohistochemically and loss of distal nerve endings can be quantified
directly. Assessment of thermal detection thresholds is used to evaluate the function of the sensory thermal pathways, but cannot discriminate
between central and peripheral lesions. Small fibre neuropathy is often associated with potentially treatable diseases and treatment of
neuropathic pain may be required.