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Mottakelighet for karies og erosjoner - genetiske aspekter
Engelsk titel: Susceptibility for caries and erosion - genetic aspects Läs online Författare: Stenshagen, Kjersti R ; Tveit, Anne Björg ; Vieira, Alexandre R ; Mulic, Aida Språk: Nor Antal referenser: 28 Dokumenttyp: Artikel UI-nummer: 17040136

Tidskrift

Aktuel Nordisk Odontologi 2017;42(1)147-155 ISSN 1902-3545 E-ISSN 2058-7538 KIBs bestånd av denna tidskrift

Sammanfattning

Individuals exposed to the same risk factors may be more or less susceptible to dental caries. After 10 years of research it is accepted that genes are involved and that the genetic contribution to increased caries prevalence is 40%. Genetic variation in enamel and saliva proteins, immune response and taste preferences interact with other risk factors and may thereby influence the caries risk. A high prevalence of dental erosion is reported. In some individuals erosive lesions will develop despite minimal acid exposure. In others no damage will occur despite extensive acid exposures. This has been observed in individuals with high consumption of acidic drinks, with reflux/ self-induced vomiting and wine tasters. The occurrence and severity of erosive lesions have been associated with polymorphisms in enamel genes.