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Årsagen til uforklaret cytopeni kan ofte findes med fokuseret DNA-sekventering
Engelsk titel: The cause of cytopenia of undetermined significance can often be found by using next generation sequencing Läs online Författare: Werner Hansen, Jakob ; Husby, Simon ; Grönbaek, Kirsten Språk: Dan Antal referenser: 25 Dokumenttyp: Översikt UI-nummer: 18010204

Tidskrift

Ugeskrift for Laeger 2017;179(20)1756-9 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Patients with persistent cytopenia are frequently referred to the haematological departments , and a diagnosis of myelodysplastic syndrome is often suspected. After routine assessment including a broad range of blood tests, bone marrow biopsy, and cytogenetics, a definite diagnosis can still not be found for some patients, although they have symptomatic cytopenia. In these cases, next generation sequencing is a valuable supplement in identifying patients with early stages of myeloid cancer.