Clinical and socio-demographic correlates of anxious distress in Asian outpatients with major depressive disorder
Engelsk titel: Clinical and socio-demographic correlates of anxious distress in Asian outpatients with major depressive disorder
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Författare:
Si, Tian-Mei
;
Sulaiman, Ahmad Hatim
;
Chen, Chia-Hui
;
Bautista,Dianne
;
Srisurapanont, Manit
;
Maneeton, Narong
;
Suttajit, Sirijit
;
Maneeton, Benchalak
;
Likhitsathian, Surinporn
;
Eurviyanukul, Kanokkwan
;
Udomratn, Pichet
;
Chan, Edwin Shih-Yen
Email: manit.s@cmu.ac.th
Språk: Eng
Antal referenser: 32
Dokumenttyp:
Artikel
UI-nummer: 18020190
Sammanfattning
Background: Anxious distress in major depressive disorder (MDD) is common and associated with
poor outcomes and management difficulties.
Aims: This post hoc analysis aimed to examine the socio-demographic and clinical correlates of anxiety
distress in Asian outpatients with MDD.
Methods: Instead of two out of five specifiers defined by the Diagnostic and Statistical Manual
Version-5, anxious distress defined in this study was operationalized as the presence of at least two
out of four proxy items drawn from the 90-item Symptom Checklist, Revised (SCL-90-R). Other measures
included the Montgomery–Asberg Depression Rating Scale (MADRS), the Fatigue Severity Scale,
the Sheehan Disability Scale and the Multidimensional Scale of Perceived Social Support.
Results: The data of 496 patients with MDD were included. Anxious distress was found in 371 participants
(74.8%). The binary logistic regression analysis found that anxious distress was independently
and significantly correlated with working status, higher MADRS scores, severe insomnia and functional
impairment.
Conclusions: Three-fourths of Asian patients with MDD in tertiary care settings may have DSM-5 anxious
distress of at least moderate distress. Its prevalence may vary among working groups. The specifier was
associated with greater depressive symptom severity, severe insomnia and functional impairment.