Engelsk titel: Anxiety and depression after breast cancer surgery can be relieved
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Författare:
Mertz, Birgitte Goldschmidt
;
Duun-Henriksen, Anne Katrine
;
Kroman, Niels
;
Johansen, Christoffer
;
Andersen, Kenneth Geving
;
Andersson, Michael
;
Mathiesen, Ulla Breitenstein
;
Vibe-Petersen, Jette
;
Dalton, Susanne Oksbjerg
;
Bidstrup, Pernille Envold
Språk: Dan
Antal referenser: 34
Dokumenttyp:
Artikel
;
RCT
UI-nummer: 18090006
Sammanfattning
Our aim was to determine the feasibility and effectiveness of an individual, nurse-navigator intervention for relieving distress, anxiety, depression and health-related quality of life in women who have been treated for breast cancer and are experiencing moderate-to-severe psychological and physical symptoms.
Methods: Fifty women with newly diagnosed breast cancer who reported distress (score ≥ 7 on distress thermometer) before surgery were included consecutively in a pilot study and randomized 1:1 to the intervention or the control group. The intervention comprised repeated screening with patient reported outcome measures and nurse navigation. A total of 66 women who were not distressed (score <7) were followed longitudinally as an observational group. Participants filled in four questionnaires, at baseline, after 6 months and 12 months. The primary outcome was psychological distress and the secondary outcomes were anxiety, depression, health-related quality of life, and feasibility of the intervention.
Results: Women in the intervention group reported significantly greater satisfaction with treatment and rehabilitation and lower levels of distress (mean 2.7 vs. 5.1, P < 0.01), anxiety (mean 5.1 vs. 7.8, P = 0.02) and depression (mean 2.2 vs. 4.4, P = 0.04) after 12 months compared to the control group. No significant effects were seen on health-related quality of life.
Conclusion: The study shows promising feasibility of the individually tailored nurse-navigation intervention and while no significant effects were observed after 6 months, we did find statistically significant effects on distress, anxiety and depression 12 months after diagnosis. Our results will assist in developing rehabilitation to the most vulnerable patients.