Toxoplasma gondii – obsessive –compulsive disorder relationship: is it different in children?
Engelsk titel: Toxoplasma gondii – obsessive –compulsive disorder relationship: is it different in children?
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Författare:
Miman, Özlem
;
Özcan, Özlem
;
Ünal, Süheyla
;
Atambay, Metin
Email: ozlem.miman@deu.edu.tr
Språk: Eng
Antal referenser: 44
Dokumenttyp:
Artikel
;
Jämförande studie
UI-nummer: 19010316
Sammanfattning
Background and aim: Obsessive–compulsive disorder (OCD) is a common neuropsychiatric illness. Although the etiology of OCD is still unknown, recent investigations have associated development of OCD with infectious illness. Toxoplasma gondii (T. gondii) is a neurotropic protozoan parasite that causes infection of the central nervous system. In the last decade, a lot of researches have focused on the possible relationship between exposure to T. gondii and neuropsychiatric disorders such as schizophrenia. Therefore, in this study, it was aimed to investigate a possible association between Toxoplasma infection and OCD in children and adolescents.
Methods: We selected 55 patients with OCD (aged between 7 and 16 years) and 59 healthy children and adolescents (aged between 7 and 16 years), and investigated the seropositivity rate for anti-Toxoplasma IgG antibodies by enzyme-linked immunosorbent assay.
Results: The seropositivity rate for anti-T. gondii IgG antibodies among OCD patients (21.82%) was found to be higher than the rate in control group (15.25%). However, the difference between the OCD group and the control group was not statistically significant (p > .05).
Conclusion: In contrast to studies in adult patients, the results of this study do not support the relationship between T. gondii and OCD children and adolescents.