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Intrakraniale meningeomer
Engelsk titel: Intracranial meningiomas Läs online Författare: Winther Kristensen, Bjarne ; Halle, Bo ; Rom Poulsen, Frantz ; Schou Andersen, Mikkel ; Bonde Pedersen, Christian ; Mathiesen, Tiit ; Poulsgaard, Lars Språk: Dan Antal referenser: 30 Dokumenttyp: Översikt UI-nummer: 19080163

Tidskrift

Ugeskrift for Laeger 2019;181(10)945-8 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Meningiomas are the most frequent intracranial non-glial tumours. They are derived from arachnoid cap cells and are classified according to WHO histology-based classification. The epigenetic technique DNA methylation profiling has shown improved prognostic value in comparison to the current WHO classification. Total surgical tumour removal is still golden standard in meningioma treatment with radiation as a supplement for WHO high-grade patients and inoperable patients. Efficient medical alternatives to surgery are not yet available, but future research may provide new strategies to be explored.