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Genetiske undersögelser i den personlige medicinaera
Engelsk titel: Genomic analyses in the personalised medicine era Läs online Författare: Örntoft, Torben Falck Språk: Dan Antal referenser: 6 Dokumenttyp: Artikel UI-nummer: 20050004

Tidskrift

Tandlaegebladet 2019;123(8)662-6 ISSN 0039-9353 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

The understanding of the human genome is now finding its way into the daily clinic in hospitals world-wide. It opens new possibilities for individualized screening, examinations, treatments and follow-up. The Danish Parliament has decided on a strategy for Personalized Medicine in Denmark. It includes the formation of a Danish National Genome Centre that will coordinate the activities, and house many of these. Up to now mainly cancer and inherited diseases have utilized genomic knowledge, however, several other diseases are now benefiting from this tool also. Risk variants in the genome can be used for screening purposes, and many diseases can be stratified into sub groups based on different genomic components. This is leading to development of new targeted medicine aimed at subgroups. There are ethical and legal challenges that need to be addressed, with the individual’s right to make his or her own decision in relation to the focus.