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Kan strålebehandling redusere frekvensen av restenose etter koronar angioplastikk?
Engelsk titel: Can radiotherapy reduce the frequency of restenosis after coronary angioplasty? Läs online Författare: Hagen S ; Langberg CW ; Solheim S Språk: Nor Antal referenser: 33 Dokumenttyp: Översikt UI-nummer: 00030365

Tidskrift

Tidsskrift for Den Norske Laegeforening 2000;120(6)707-10 ISSN 0029-2001 E-ISSN 0807-7096 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

X : Today, percutaneous transluminal coronary angioplasty (PTCA) is the most important treatment modality for coronary artery disease. However, restenosis occurs in 20-40% of the vessels in spite of the use of stents. Intravascular radiation therapy has reduced the frequency of restenosis in both animal studies and clinical trials. Recent randomized trials have shown a reduction in the order of 30% after irradiation. A number of techniques which use different sources of radiation (beta vs. gamma radiation) are under investigation. This review gives and update of intravascular radiation therapy, including a discussion of ongoing trials. There is a great need, also in Norway, for treatment modalities that reduce the frequency of restenosis after PTCA. It would seem imperative that we start a discussion of whether and when intravascular radiation therapy should be available in Norway. Implementation requires planning on a national level with regard to investment in equipment and training.