Engelsk titel: Cluster headache - clinical findings, pathophysiology and treatment
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Författare:
Salvesen R
Språk: Nor
Antal referenser: 41
Dokumenttyp:
Översikt
UI-nummer: 01039616
Sammanfattning
EPIDEMIOLOGY : Cluster headache afflicts somewhat less than one in thousand in the general population. The majority of sufferers are men.
CLINICAL FEATURES : The syndrome is characterized by frequent attacks of intense pain localized in and around the eye on one side, characteristically accompanied by conjunctival injection and lacrimation in this eye, along with nasal stuffiness on the same side and sometimes a Horner's syndrome. All symptoms and signs are strictly unilateral and occur during attacks lasting between 15 minutes and three hours. The attacks occur from once to eight times daily during a period lasting from some weeks to months. After a remission of varying duration, the same pattern recurs.
PATHOPHYSIOLOGY : Recent findings suggest a pivotal role of the hypothalamus in relation to the pathophysiology.
TREATMENT : Sumatriptan injection or oxygen inhalation aborts pain attacks in most patients. The most frequently used prophylactic agents are verapamil, lithium and steroids.