Sök artiklar i SveMed+

Observera: SveMed+ upphör att uppdateras!



Tuberkulose hos HIV-smittede i Norge
Engelsk titel: Tuberculosis among HIV-infected persons in Norway Läs online Författare: Ormaasen V ; Maeland A Språk: Nor Antal referenser: 40 Dokumenttyp: Översikt UI-nummer: 02011500

Tidskrift

Tidsskrift for Den Norske Laegeforening 2001;121(29)3425-30 ISSN 0029-2001 E-ISSN 0807-7096 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

BACKGROUND : HIV-infected persons have a considerably higher risk of developing active tuberculosis than immunocompetent individuals. Tuberculosis is the only opportunistic infection among HIV-infected persons that presents a potential health risk to the general population. MATERIAL AND METHODS : We present a review on this topic based on relevant literature and clinical experience. RESULTS : Treatment options are limited because of interactions between rifamycins and protease inhibitors and non-nucleoside analogues. When concomitant therapy against HIV infection and tuberculosis is indicated, we suggest a first-line regimen of rifabutin combined with either indinavir or nelfinavir. For patients without severe immunodeficiency, anti-retroviral therapy can be postponed until the end of the initial phase of the anti-tuberculosis treatment. INTERPRETATION : Treatment of concurrent HIV infection and tuberculosis is complex and may involve multiple drug regimens. Treating the latent infection could in many cases prevent active tuberculosis. All HIV-infected persons should be evaluated with respect to active tuberculosis and latent infection.