Engelsk titel: Molecular biological focus on stem cell research
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Författare:
Ebbesen P
Språk: Dan
Antal referenser: 10
Dokumenttyp:
Artikel
UI-nummer: 03021154
Sammanfattning
Stem cells are defined by their capacity to reproduce themselves and to differentiate into many other cell types. Differentiation requires external signals and involves activation of a small number of genes. Which source of stems cell will eventually be used in the clinic has not yet been determined. Embryonic stem cells have unlimited in vitro division capa-city and can differentiate to all cell types, but there may be a problem with genomic instability. Stem cells from cord blood and adult tissue seem to have limited in vitro division and differentiation potential, but stable genomes.