Endotelinreceptorblokering med bosentan - et nyt behandlingsprincip ved pulmonal arteriel hypertension
Engelsk titel: Blockade of endothelin receptor with bosentan - a new principle of treatment in pulmonary arterial hypertension
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Författare:
Nielsen-Kudsk JE
Email: jenk@dadlnet.dk
Språk: Dan
Antal referenser: 8
Dokumenttyp:
Översikt
UI-nummer: 03071064
Sammanfattning
Blockade of endothelin receptors is a new drug principle for the treatment of pulmonary arterial hypertension. Bosentan is a competitive blocker of endothelin receptors administered by the oral route. In clinical trials it has been shown to increase the functional capacity of patients with pulmonary arterial hypertension. This article describes the background, results of clinical trials, and practical guidelines for the use of bosentan in pulmonary arterial hypertension.