Engelsk titel: Pegylated interferon-alpha for the treatment of chronic hepatitis C
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Författare:
Weis NM
;
Krarup HB
;
Skinhöj P
Språk: Dan
Antal referenser: 36
Dokumenttyp:
Översikt
UI-nummer: 03111681
Sammanfattning
Interferon-a (IFN-a) has since the early 1990s been an important component in the treatment of chronic hepatitis C. The therapeutical effect is limited, among other causes because IFN-a is rapidly metabolised and eliminated from the organism. The binding of polyethylene glycol units to proteins, as e.g. IFN-a, protects the proteins against destruction and thereby enhances their therapeutical effect. The purpose of this article is to provide information about the use of pegylated IFN-a in the treatment of patients with chronic hepatitis C.