Forebyggelse af Rhesusimmunisering. II. Imödegåelse af risiko i sidste halvdel af graviditeten og ved födslen
Engelsk titel: Prevention of Rh immunisation. II. Management of the risk during the second half of pregnancy and postpartum
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Författare:
Falck Larsen J
;
Bock JE
;
Jörgensen JR
Email: falcklarsen@dadlnet.dk
Språk: Dan
Antal referenser: 35
Dokumenttyp:
Översikt
UI-nummer: 04081010
Sammanfattning
Based on evidence from the literature, the following guidelines are recommended: 100 µg of IgG anti-D should be given within 72 hours of delivery to non-sensitised rhesus-negative women. Additional IgG anti-D should be given if a feto-maternal haemorrhage greater than 4 ml foetal erythrocytes is detected. Antenatal prophylaxis is recommended for all rhesus-negative women, with two injections of 100 µg of IgG anti-D at 28 and 34 weeks. Amniocentesis and chordocentesis, as well as external version of the fetus, should be performed in rhesus-negative women only if the indication is very strong. In these cases 100 µg of IgG anti-D should be given. In the case of severe abdominal injury in pregnancy, anti-D should be considered.