Sök artiklar i SveMed+

Tidskrift

Sammanfattning

Introduction: Renovascular hypertension (RH) is potentially curable. For many years, renal vein renin sampling (RVRS) has been one of the main diagnostic procedures for the evaluation of patients suspected of having RH. Recently the efficacy of the test has been disputed. The aim of the present study was to analyse the outcome of RVRS in patients with suspected RH. Materials and methods: 98 consecutive patients were included over an eight-year period. Twenty-seven of them had abnormal RVRS. It was not possible to follow up on two of the patients. In the remaining 25 patients, the blood pressure and the type of medical versus surgical therapy was recorded. Results: Ten patients (40%) underwent revascularization (none of the stenoses was caused by fibromuscular dysplasia). Arterial blood pressure was normalised in one patient, improved in seven and two had a doubtful effect. Seven patients (28%) were nephrectomised. As far as blood pressure was concerned, five of them improved and two showed a doubtful effect. Antihypertensive drugs were the only treatment for eight patients (32%). The blood pressure was still increased at the end of the follow-up period in three of the ten patients who underwent revascularization, in two of the seven who were nephrectomised and in three out of the eight who were treated with antihypertensive drugs. Discussion: The rate of cure is low in patients with RH. RVRS does not seem to be the ideal diagnostic tool in the identification of patients whose blood pressure is likely to decrease after successful invasive treatment of RH.

MeSH