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Levercirrose og bakterielle infektioner
Engelsk titel: Liver cirrhosis and bacterial infections Läs online Författare: Vilstrup H Språk: Dan Antal referenser: 11 Dokumenttyp: Artikel UI-nummer: 05021115

Tidskrift

Ugeskrift for Laeger 2005;167(7)739-41 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

The mortality rate of infections in patients with cirrhosis is more than 20 times that in the general population. Both the host's defense system and the systemic response to infection are compromised, and the microbiotic invasion, often of an opportunistic nature, is augmented due to intestinal translocation, aspiration, and other factors. Infection should be suspected in any cirrhotic patient with a deteriorating clinical course, and treatment with large doses of broad-spectrum anti biotics, avoiding aminoglycosides, should be promptly initiated. Antibiotic prophylaxis carries a high risk of colonization with resistant strains but reduces the mortality rate from upper gastrointestinal bleeding and recurrent spontaneous bacterial peritonitis.