Historien om kolbötten med hormonbrug og hjerte-kar-sygdomme
Engelsk titel: The story of the reversal of opinion about hormone therapy and cardiovascular disease
Läs online
Författare:
Lökkegaard EC
Email: loekkegaard@dadlnet.dk
Språk: Dan
Antal referenser: 10
Dokumenttyp:
Artikel
UI-nummer: 05031300
Sammanfattning
This is the story of the reversal of opinion concerning the relationship between hormone therapy and cardiovascular disease. Hormone therapy has been used for more than 50 years to alleviate climacteric symptoms. Epidemiologic studies have suggested that hormone therapy protects against the development of cardiovascular disease, whereas recent randomised clinical trials have suggested an opposite effect. This article discusses the methodological issues and biological concerns that may explain the discrepant findings. Results from Danish studies are summarized.