Forholdet mellem placebovirkning og spontan bedring i antidepressive forsög. Er placebo krafteslös?
Engelsk titel: The relationship between the placebo effect and spontaneous improvement in research on antidepressants. Are placebos powerless?
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Författare:
Hougaard E
Email: esbenh@psy.au.dk
Språk: Dan
Antal referenser: 39
Dokumenttyp:
Översikt
UI-nummer: 05081282
Sammanfattning
Clinical trials of antidepressant medications have generally found large changes in groups given a placebo, which may be due to either spontaneous remission or a true placebo effect. This paper reviews the evidence for a true placebo effect in the treatment of unipolar depressed outpatients. Although there is no evidence from experimental studies, a rather substantial amount of circumstantial evidence indicates a true placebo effect. This article raises the question of whether it is meaningful to require experimental evidence for a loose and unspecified concept involving varying components such as placebo.