Ginseng modulerer immunresponset via påvirkning af cytokinproduktionen - sekundaerpublikation
Sammanfattning
Ginseng has been shown to modulate the immune system. In this study, ginseng's effects against chronic P. aeruginosa lung infection in animal models and its cytokine-modulating effects on leukocytes were investigated. Leukocytes cultured with ginseng produced more interleukin-12. Animal models treated with ginseng s.c. showed a much faster bacterial clearance, milder lung pathology, activation of phagocytes and a Th1 immune response. These results suggest that ginseng treatment induced a Th1-like immune response, which improved the pathologic course in our animal models.