Engelsk titel: Glucocorticoids reduce acute postoperative pain
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Författare:
Romundstad L
;
Breivik H
;
Stubhaug A
Email: luisro@medisin.uio.no
Språk: Nor
Antal referenser: 32
Dokumenttyp:
Artikel
UI-nummer: 05091679
Sammanfattning
X : Glucocorticoids have been used for postsurgical pain relief over the last 30 years. They reduce prostaglandins by inhibiting phospholipase A2 and the expression of COX-2 mRNA. The evidence for an analgesic effect is best after oral, orthopaedic, laparoscopic and perianal surgery. Their anti-emetic properties in addition to the analgesic effects make them particularly useful perioperatively.