Duloxetin. Et nyt praeparat til patienter med urininkontinens
Engelsk titel: Duloxetine. A new preparation for patients with urinary incontinence
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Författare:
Walter S
Email: steen.walter@ouh.fyns-amt.dk
Språk: Dan
Antal referenser: 6
Dokumenttyp:
Artikel
UI-nummer: 05111132
Sammanfattning
Stress Urinary Incontinence is a common symptom among women. The urethral closure is insufficient. Pelvic floor exercise can minish the symptoms, but many women need an operation. Duloxetine, a new drug, is believed to strengthen the contraction of the external urethral sphincter through central neuromodulation, resulting in enhanced urethral closure during the urine storage phase. In controlled studies a significant effect are found in women suffer from Stress Urinary Incontinence. Discontinuate rates for adverse events were high especially nausea and fatique. The adverse event deminish after 4 weeks.