Behandling af svaer sarkoidose med tumornekrosefaktor alpha-haemmer (infliximab)
Engelsk titel: Treatment of severe sarcoidosis using a TNF inhibitor (infliximab)
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Författare:
Milman N
;
Brandt Sörensen T
Email: milman@rh.dk
Språk: Dan
Antal referenser: 5
Dokumenttyp:
Fallbeskrivning
UI-nummer: 06021497
Sammanfattning
Some patients with severe sarcoidosis are resistant to conventional treatment with corticosteroids and cytostatics. We describe a 29-year-old man with histologically verified sarcoidosis and persistent, pronounced enlargement of the peripheral lymph nodes, resistant to treatment with prednisolone and methotrexate. Following treatment with TNF-a -inhibitor (infliximab 3 mg/kg body weight), the lymph nodes regressed to normal size and the patient improved clinically. The patient had a total of four infliximab infusions, and the effect has persisted for more than two years.