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Allergiudredning i almen praksis i Århus Amt. Kvalitetsvurdering af diagnostik, behandling og patientinstruktion III: Allergidiagnostik
Engelsk titel: Allergy in general practice in the county of Århus. Quality assessment of diagnosis, treatment and instructions to patients III. Allergy testing Läs online Författare: Korsgaard Jensen J ; Klitgaard Jakobsen M Språk: Dan Antal referenser: 13 Dokumenttyp: Artikel UI-nummer: 06041969

Tidskrift

Ugeskrift for Laeger 2006;168(13)1336-40 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

Introduction: The aim of this study was to compare the allergy test with the skin prick test and the specific IgE by Phadiatop test to a purely clinical allergy diagnosis by an allergy specialist in adult patients previously tested in general practice. Materials and methods: A total of 103 patients suspected of having asthma and/or rhinitis were re-evaluated with a clinical diagnosis and the two allergy tests. Both the patient and the individual general practitioner were asked about existing allergy diagnosis. Results: The two test systems showed large differences in a semiquantitative linear system with an explained variation (r2 ) of only 8%. In comparison to a purely clinical diagnosis, they were diagnostically equal with both tests, with an additional 15% positive reactions of which 25% were judged clinically active. Both tests resulted in about 33% false-positive tests classified as clinically inactive. In the case of a positive Phadiatop test and clinically active allergy, both the patient and the general practioner reported identical specialist diagnoses in about 75% of cases, while in 20-50% of the cases an identical diagnosis was reported when the clinical diagnosis was qualitatively different from the result of Phadiatop. Conclusion: The results of the two test systems often differ, and they both detect extra positive tests, in which case they should be used in a serial manner. Both tests often result in a false-positive diagnosis, and identification of clinically relevant positive tests often requires an experienced medical evaluation.