Engelsk titel: Probiotics - should we change the treatment strategy for pouchitis?
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Författare:
Klinge LG
;
Kjeldsen J
Email: lone.klinge@ouh.fyns-amt.dk
Språk: Dan
Antal referenser: 12
Dokumenttyp:
Översikt
UI-nummer: 06101100
Sammanfattning
Pouchitis is an idiopathic inflammatory bowel disease, which occurs in up to 50% of patients operated on for ulcerative colitis with ileal pouch-anal anastomosis (IPAA). Treatment of pouchitis is still to a large extent empirical, but recently more randomized, double-blind placebo-controlled trials have been conducted. This article reviews the possible treatments for pouchitis, focusing especially on treatment with probiotics, which seem to be a new and promising alternative to antibiotics. We are currently doing clinical trials to determine whether a probiotic is an effective treatment for chronic inflammatory bowel disease.