Engelsk titel: Treatment of hepatitis C virus infection in patients with concurrent HIV infection
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Författare:
Peters L
;
Lindhardt BÖ
Email: larspeters@dadlnet.dk
Språk: Dan
Antal referenser: 38
Dokumenttyp:
Översikt
UI-nummer: 06101155
Sammanfattning
Coinfection with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) is frequent. While it is still unclear whether HCV affects the course of HIV infection, there is ample evidence that concurrent HIV infection accelerates the progression of fibrosis and liver-related morbidity and mortality in HCV-infected patients. The treatment of HCV infection in patients with HIV/HCV coinfection has improved during the last few years, but the outcome appears to be poorer than the outcome in HCV monoinfected patients. In this article the epidemiological and clinical aspects of HCV/HIV coinfection are described, and the four major treatment trials are reviewed.