Cochraneoversigter sammenlignet med firmastöttede og andre metaanalyser af de samme laegemidler - sekundaerpublikation
Engelsk titel: Cochrane reviews compared with industry-supported and other meta-analyses of the same drugs - secondary publication
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Författare:
Jörgensen AW
;
Hilden J
;
Götzsche PC
Email: pcg@cochrane.dk
Språk: Dan
Antal referenser: 8
Dokumenttyp:
Översikt
UI-nummer: 06121432
Sammanfattning
24 Cochrane reviews were compared with other, closely matched, meta-analyses of the same drugs. The quality score was highest for Cochrane reviews (7 vs. 2, p < 0.01). Of 8 industry-supported reviews, 7 with conclusions all recommended the experimental drug without reservations, compared with none of the Cochrane reviews (p = 0.02) although the estimated treatment effect was similar on average (p = 0.64). Industry-supported reviews were less transparent, had few reservations about methodological limitations of the included trials, and should be read with caution.