Sammanfattning
RESULTS AND INTERPRETATION : 100 ovarian stimulation-cycles for TESE-CSI have been performed at our clinic. This has led to 82 Embryo Transfers (ET) using fresh embryos and 40 ET using frozen/thawed embryos. 39 clinical pregnancies have been achieved. Thus, there is a 39% chance for pregnancy per started stimulation-cycle. These results are comparable to those from ICSI using ejaculated sperm cells. The TESE-ICSI treatment seems to be a good method to help couples become genetic parents when the man presents azoospermia.
MATERIAL AND METHODS : 94 couples (man with azoospermia) who had undergone examination and work-up at Fertilitetsklinikken Sør in the period 2004-06, were followed. Of these couples, 60 had been treated with TESE-ICSI. TESE is performed in an out-patient setting under local anaesthesia as an open testicular biopsy. By a special technique, sperm cells are retrieved from the biopsy and then used for fertilizing oocytes from the partner.
BACKGROUND : Couples where the man presents azoospermia, could not be helped to become genetic parents by assisted reproduction in Norway until recently. A temporary permission to perform techniques that can help these couples was granted with a change in the Norwegian laws on biotechnology in 2004. Our experience with intra cytoplasmic sperm injection (ICSI) using sperm retrieved by testicular sperm extraction (TESE) is presented.