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Ny operationsmetod hjälper infertila män bli biologiska fäder. Mikro-TESE kan vara ett sista hopp för män med icke-obstruktiv azoospermi
Engelsk titel: Microdissection testicular sperm extraction (MD-TESE) – a new sperm recovery technique helping men with non-obstructive azoospermia Läs online Författare: Westlander, Göran ; Schmidt, Johanna ; Westin, Cecilia Språk: Swe Antal referenser: 11 Dokumenttyp: Översikt UI-nummer: 19090205

Tidskrift

Läkartidningen 2019;116(30-32)1212-5 ISSN 0023-7205 E-ISSN 1652-7518 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

The most severe form of male infertility is non obstructive azoospermia (NOA), where spermatogenesis is impaired or absent. If testicular sperm can be retrieved, men with NOA can become biological fathers with IVF/ ICSI. In Sweden, testicular sperm aspiration (TESA) is the most common method used to retrieve sperm but is only successful in up to 34% of procedures. In 2013, our fertility center introduced MD-TESE, where an operating microscope is used to target the biopsies. We have performed more than 134 MD-TESE procedures, mainly in cases where TESA sperm recovery failed previously. Sperm sufficient for ICSI were recovered in 52 % and in these cases 75 % resulted in embryo transfer, resulting in a 34 % ongoing pregnancy rate/deliveries per transfer. Results are encouraging and hopefully more Swedish IVF centers will introduce this technique.