Sök artiklar i SveMed+

Observera: SveMed+ upphör att uppdateras!



Komplet remission efter rituximabbehandling ved refraktaer hårcelleleukaemi
Engelsk titel: Complete remission after rituximab treatment in refractory hairy cell leukemia Läs online Författare: Petruskevicius I ; Bukh A ; Mertz H ; Johnsen E Språk: Dan Antal referenser: 5 Dokumenttyp: Fallbeskrivning UI-nummer: 08071415

Tidskrift

Ugeskrift for Laeger 2008;170(26-32)2350 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

A 40-year-old man with hairy cell leukemia (HCL) was treated with Cladribin, but achieved only partial response (PR). As expected, both 2 and 5 years later the disease had progressed and the patient was therefore twice retreated with Cladribin. A bone marrow examination after the last Cladribin course showed complete response with residual disease (CR-RD). The patient received consolidation therapy with Rituximab, achieved complete response (CR) and was still in CR 9 months later. Rituximab is a good treatment option for patients with refractory HCL because of its significant activity and minimal toxicity.