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Tourettes syndrom. Genetik, neuroanatomi og neurotransmittere
Engelsk titel: Tourette syndrome. Genetics, neuroanatomy and neurotransmitters Läs online Författare: Debes NM ; Skov L ; Hjalgrim H Språk: Dan Antal referenser: 40 Dokumenttyp: Översikt UI-nummer: 08091832

Tidskrift

Ugeskrift for Laeger 2008;170(35)2695-700 ISSN 0041-5782 E-ISSN 1603-6824 KIBs bestånd av denna tidskrift Denna tidskrift är expertgranskad (Peer-Reviewed)

Sammanfattning

The etiology and pathophysiology of Tourette syndrome (TS) have not yet been clarified. Despite inconsistencies in the literature, some conclusions can be drawn on genetics, neuroanatomy and neurotransmitters. The inheritance of TS is unknown; the etiology seems to be polygenic. The basal ganglia are probably smaller in patients with TS. A dysfunction in the dopaminergic pathway causes tics. ADHD results from a decreased concentration of dopamine and an increased concentration of noradrenaline. OCD is caused by a dysfunction in serotonin and probably dopamine.